DNA
Star

Part:BBa_K1218026:Design

Designed by: Simon Vecchioni   Group: iGEM13_Stanford-Brown   (2013-09-17)

32bp10CC Duplex Nanowire


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Design Notes

The design of this piece produces a cytosine-mismatched, silver-intercalating, DNA-based nanowires. As such, the use of restriction sites and pre-designed primers were incorporated. These factors and their respective functionalities are documented on the main page.

Source

This part is entirely synthetic and cloned from an oligonucleotide sequence synthesized by Elim Biopharmaceuticals. The design is based off research done by the Akira Ono group.

Ono, Akira, Hidetaka Torigoe, Yoshiyuki Tanaka, and Itaru Okamoto. "Binding of Metal Ions by Pyrimidine Base Pairs in DNA Duplexes." Chemical Society Reviews 40 (2011): 5855-5866.

References